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1.
Rev. esp. cir. oral maxilofac ; 30(3): 201-204, mayo-jun. 2008. ilus
Artigo em Espanhol | IBECS | ID: ibc-74683

RESUMO

El adenoma pleomorfo es un tumor benigno de las glándulas salivaresformado por la combinación de elementos epiteliales y mesenquimales.Generalmente constituyen el 60-70% de los tumores de la glándula parótiday el 40-60% de los de glándula submaxilar. Menos frecuentemente essu desarrollo a partir de una glándula salivar menor, presentándose comouna masa intraoral dependiente de paladar o labio. Se expone el caso de unadenoma pleomorfo gigante de paladar duro y su exéresis por la vía transoral(AU)


Pleomorphic adenoma is a benign tumor of the salivaryglands that consists of a combination of epithelial and mesenchymalelements. The tumor most commonly arises from the parotid (60-70%) or submandibular glands. It develops less frequently on aminor salivary gland, presenting as an intraoral mass dependenton the palate or lip. A case is reported of giant pleomorphic adenomaresected using a transoral approach(AU)


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Adenoma Pleomorfo/cirurgia , Neoplasias das Glândulas Salivares/cirurgia , Palato Duro/patologia , Espectroscopia de Ressonância Magnética
2.
Acta Otorrinolaringol Esp ; 57(5): 199-203, 2006 May.
Artigo em Espanhol | MEDLINE | ID: mdl-16768196

RESUMO

OBJECTIVE: The purpose of this study is the identification of susceptible individuals to develop noise induced hearing loss. For it we use the capacity of the transitory otoacoustic emissions (TEOAE) for the identification of functional alterations at different levels from the auditory system. MATERIAL AND METHODS: 67 normal hearing subjects have been studied, we have recorded TEOAE in one ear in three different conditions: in normal conditions (SIN register), simultaneously to the stimulation of the contralateral cochlea (EAC register), and after stimulation we can observe (EAI register). We compare the amplitude of the TEOAE with the SIN and EAC registers to quantity the contralateral suppresor effect, and the SIN and EAI, register to study the auditory fatigue. RESULTS: We can observe a reduction in the amplitude of the TEOAE obtained by acoustic stimulation of the ipsilateral ear (0.954 dB SPL), or after the ipsilateral acoustic stimulation (0.75 dB SPL), being able to see an inverse correlation between both values. CONCLUSIONS: The study of the TEOAE obtained in different conditions of acoustic stimulation, ipsilateral or contralateral, and the inverse correlation obtained between the magnitude of the auditory fatigue and the contralateral suppresor effect, provides arguments for the identification of individuals susceptible of developing noise induced hearing loss.


Assuntos
Fadiga Auditiva , Emissões Otoacústicas Espontâneas , Adolescente , Adulto , Feminino , Humanos , Masculino
3.
Acta otorrinolaringol. esp ; 57(5): 199-203, mayo 2006. ilus
Artigo em Es | IBECS | ID: ibc-045668

RESUMO

Objetivos: La finalidad de este estudio es la identificación de individuos susceptibles al desarrollo de hipoacusia neurosensorial inducida por ruido. Para ello aprovechamos la capacidad de las otoemisiones acústicas transitorias (TEOAE) para la identificación de alteraciones funcionales a distintos niveles de la vía auditiva. Material y métodos: Se han estudiado 67 sujetos normooyentes, obteniendo TEOAE en un oído en tres condiciones diferentes: en condiciones habituales (Registro SIN), simultáneamente a la estimulación de la cóclea contralateral (Registro EAC), y tras la estimulación ipsilateral (Registro EAI). Comparamos la amplitud de las TEOAE de los registros SIN y EAC para la cuantificación del efecto supresor contralateral, y la de los registros SIN y EAI, para el estudio de la fatiga auditiva. Resultados: Se objetiva una reducción en la amplitud de las TEOAE obtenidas simultáneamente a una estimulación acústica contralateral (0,954 dB SPL), o tras la estimulación acústica ipsilateral (0,75 dB SPL, observándose una correlación inversa entre ambos valores. Conclusiones: El estudio de las TEOAE obtenidas en diferentes condiciones de estimulación acústica, ipsilateral o contralateral, y la correlación inversa obtenida entre la magnitud de la fatiga auditiva y el efecto supresor contralateral proporciona argumentos para la identificación de individuos susceptibles al desarrollo de hipoacusia tras la exposición al ruido


Objective: The purpose of this study is the identification of susceptible individuals to develop noise induced hearing loss. For it we use the capacity of the transitory otoacoustic emissions (TEOAE) for the identification of functional alterations at different levels from the auditory system. Material and methods: 67 normal hearing subjects have been studied, we have recorded TEOAE in one ear in three different conditions: in normal conditions (SIN register), simultaneously to the stimulation of the contralateral cochlea (EAC register), and after stimulation we can observe (EAI register). We compare the amplitude of the TEOAE with the SIN and EAC registers to quantity the contralateral suppresor effect, and the SIN and EAI, register to study the auditory fatigue. Results: We can observe a reduction in the amplitude of the TEOAE obtained by acoustic stimulation of the ipsilateral ear (0.954 dB SPL), or after the ipsilateral acoustic stimulation (0.75 dB SPL), being able to see an inverse correlation between both values. Conclusions: The study of the TEOAE obtained in different conditions of acoustic stimulation, ipsilateral or contralateral, and the inverse correlation obtained between the magnitude of the auditory fatigue and the contralateral suppresor effect, provides arguments for the identification of individuals susceptible of developing noise induced hearing loss


Assuntos
Adulto , Masculino , Feminino , Humanos , Fadiga Auditiva , Emissões Otoacústicas Espontâneas , Perda Auditiva Neurossensorial/diagnóstico , Cóclea/anatomia & histologia , Cóclea/patologia
4.
Acta Otorrinolaringol Esp ; 56(4): 179-80, 2005 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-15871295

RESUMO

Hearing loss must be easily calculated by mean of the rules of actual legislation on handicap. It is just necessary to know the hearing thresholds for 500, 1000, 2000 and 4000 Hz tones. Calculation of a linear regression equation allows to obtain quickly hearing loss average from these thresholds.


Assuntos
Perda Auditiva/diagnóstico , Audiometria , Humanos , Modelos Lineares , Fatores de Tempo
5.
Acta otorrinolaringol. esp ; 56(4): 179-180, abr. 2005. ilus
Artigo em Es | IBECS | ID: ibc-038159

RESUMO

La pérdida auditiva puede ser fácilmente calculada mediante las pautas referidas en la legislación vigente sobre minusvalías. Basta conocer los umbrales auditivos en las frecuencias en 500, 1000, 2000 y 3000 Hz. La obtención de una ecuación de regresión lineal permite conocer rápidamente el porcentaje de pérdida auditiva a partir de estos umbrales


Hearing loss must be easily calculated by mean of the rules of actual legislation on handicap. It is just necessary to know the hearing thresholds for 500, 1000, 2000 and 4000 Hz tones. Calculation of a linear regression equation allows to obtain quickly hearing loss average from these thresholds


Assuntos
Humanos , Perda Auditiva/diagnóstico , Audiometria/métodos , Testes Auditivos/métodos , 16136
6.
Acta Otorrinolaringol Esp ; 54(3): 233-5, 2003 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-12825347

RESUMO

We report the case of a 29 year-old male with of hereditary spherocytosis, who developed two episodes of sensorineural hearing loss in his right ear after splenectomy due to repetitive hemolytic crisis. We discuss the eventual altiopathogenic mechanism of this audiological disorder.


Assuntos
Perda Auditiva Súbita/etiologia , Complicações Pós-Operatórias , Esferocitose Hereditária/cirurgia , Adulto , Humanos , Masculino
7.
Acta Otorrinolaringol Esp ; 54(2): 109-12, 2003 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-12802986

RESUMO

The higher incidence of immunosuppressive status is increasing in the last years the diagnosis of tumours of unusual location and behaviour. We present the case of a HIV-seropositive 41 years-old woman, bearing of high dysphagia and pharyngolalic voice. The exploration showed a tumour emerging in lingual tonsil and spreading out to hypopharynx and larynx. No lymph nodes were observed. Its resistance to chemotherapy made necessary its surgical removal.


Assuntos
Linfoma de Burkitt , Transtornos de Deglutição/etiologia , Tonsila Palatina/patologia , Adulto , Linfoma de Burkitt/complicações , Linfoma de Burkitt/tratamento farmacológico , Linfoma de Burkitt/patologia , Resistencia a Medicamentos Antineoplásicos , Feminino , Soropositividade para HIV/complicações , Humanos
8.
Rev. esp. pediatr. (Ed. impr.) ; 59(3): 208-214, mayo-jun. 2003. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-119727

RESUMO

Introducción. Nuestro objetivo fue comparar el curso evolutivo y la respuesta al tratamiento quirúrgico en la enfermedad adenoamigdalar en niños con síndrome de Down (SD) y en un grupo de control. Pacientes y métodos. En 28 niños con SD y en 56 controles sanos intervenidos mediante amigdalectomía con/sin adenoidectomía se evaluó la indicación, las características microbiológicas y oxidativas del tejido linfoide, las circunstancias del acto quirúrgico y las eventuales complicaciones y evolución clínica postoperatorias. Resultados. Los niños con SD son principalmente intervenidos por hipertrofia amigdalar (los controles, por amigdalitis de repetición). Entre los niños con SD los títulos de antiestreptolisinas y antioxidantes, así como el número de aislamientos microbiológicos, resultaron significativamente inferiores a los controles. La intervención no condicionó especiales complicaciones en ningún grupo. En niños con SD el alivio en el ronquido y la faringolalia fue inferior, debido a otras anomalías constitucionales en rinofaringe e hipofaringe, pero las pausas de apnea durante el sueño y la expresividad oral mejoraron de forma llamativa. Conclusiones. La hipertrofia amigdalar es un dato que el pediatra debe verificar y remitir al especialista otorrinolaringólogo en situaciones de síndrome de apnea obstructiva, dificultad en la comunicación verbal, trastornos deglutorios e incluso reflujo gastroesofágico (AU)


Introduction. Our aim was to compare the evolutive course and response to surgery in adenotonsillar disease in children with Down´s syndrome (DS) and in a control group. Patients and methods. 28 cases with DS and 56 healthy controls were submitted to tonsillectomy with or without adenoidectomy. An evaluation of surgical indications, bacteriological and oxidative findings of lymphoid tissue and of surgery was carried-out. The eventual postoperative complications and the clinical follow-up was also controlled. Results. Children with DS were mainly operated due to tonsillar hyperthorphy. In controls, surgery was performed usually due to recidivant tonsillitis. Among DS children, antistreptolysin and antioxidant levels, and the number of bacteriological isolations were significantly lower than in controls. Surgery did not provoke serious complications in any group. In children with DS, there was a lesser ameliotation in snoring and pharyngolalia, due to other constitutive anomalies in naso-and hypopharynx, buth sleep apnoea episodes and capacity of oral expression improved to a high degree. Conclusions. Tonsillar hypertrophy is a finding that paediatricians must verify and send to ENT surgeon in circumstances of obstructive sleep apnoea, difficulties in oral communications, swallowing disorders and even gastroesophageal reflux (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Síndrome de Down/complicações , Tonsilectomia/estatística & dados numéricos , Tonsilite/cirurgia , Estudos de Casos e Controles , Adenoidectomia/estatística & dados numéricos , Apneia/epidemiologia , Resultado do Tratamento , Estudos Prospectivos
9.
Acta Otolaryngol ; 123(2): 168-71, 2003 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-12701734

RESUMO

OBJECTIVE: To identify autoantibody bands using Western blotting in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). MATERIAL AND METHODS: All patients admitted to our emergency ward with ISSNHL during a 3-year period (n = 51) were included in a diagnostic laboratory protocol, which included a non-specific test battery for immune disorders and a Western blot (WB) for bovine cochlear antigen, and underwent corticosteroid therapy. RESULTS: In 16 cases (31%) a band was identified in the WB. Cases with a positive WB showed abnormal results in a greater number of non-specific laboratory tests (3.6 +/- 1.3 vs 0.9 +/- 1.1; p < 0.001) and had greater hearing recovery (33.8% +/- 17.7% vs 50.6% +/- 18.5%; p < 0.01). Moreover, patients with a positive WB showed good correlations between the degree of hearing recovery and both early onset of treatment (0.5504x + 43.621; R2 = 0.8603; p < 0.01) and age (0.4053x + 56.298; R2 = 0.8952; p < 0.01). The non-specific test battery showed a sensitivity of 78% and a specificity of 94% for detecting an autoimmune disorder compared with WB. CONCLUSION: A positive WB predicts a good response to corticosteroid therapy in ISSNHL patients. If it is not possible to perform a WB then the non-specific test battery has a good capability for predicting autoimmune disorders.


Assuntos
Autoanticorpos/análise , Doenças Autoimunes/complicações , Western Blotting , Perda Auditiva Neurossensorial/diagnóstico , Perda Auditiva Neurossensorial/imunologia , Perda Auditiva Súbita/diagnóstico , Perda Auditiva Súbita/imunologia , Corticosteroides/uso terapêutico , Adulto , Audiometria/métodos , Doenças Autoimunes/diagnóstico , Estudos de Coortes , Feminino , Perda Auditiva Neurossensorial/tratamento farmacológico , Perda Auditiva Súbita/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Valor Preditivo dos Testes , Probabilidade , Prognóstico , Análise de Regressão , Sensibilidade e Especificidade
10.
Acta otorrinolaringol. esp ; 54(3): 233-235, mar. 2003. ilus
Artigo em Es | IBECS | ID: ibc-21545

RESUMO

Presentamos el caso de un varón de 29 años afecto de esferocitosis hereditaria que desarrolló dos episodios de sordera súbita neurosensorial en oído derecho tras esplenectomía por crisis hemolíticas de repetición. Se discute el posible mecanismo etiopatogénico del trastorno audiológico (AU)


We report the case of a 29 year-old male with of hereditary spherocytosis, who developed two episodes of sensorineural hearing loss in his right ear after splenectomy due to repetitive hemolytic crisis. We discuss the eventual altiopathogenic mechanism of this audiological disorder (AU)


Assuntos
Adulto , Masculino , Humanos , Complicações Pós-Operatórias , Esferocitose Hereditária/cirurgia , Perda Auditiva Súbita/etiologia
11.
Acta otorrinolaringol. esp ; 54(2): 109-112, feb. 2003. ilus
Artigo em Es | IBECS | ID: ibc-21157

RESUMO

La creciente incidencia de estados inmunosupresores viene facilitando en los últimos años la aparición de tumores de localización y comportamiento infrecuentes. Se presenta el caso de una mujer de 41 años VIH-positiva que consultó por disfagia alta y voz faringolálica. La exploración detectó una tumoración dependiente de la amígdala lingual con extensión a hipofaringe y laringe, sin afectación adenopática. Su resistencia al protocolo quimioterápico obligó a su exéresis quirúrgica (AU)


The higher incidence of immunosuppressive status is increasing in the last years the diagnosis of tumours of unusual location and behaviour. We present the case of a HIV-seropositive 41 years-old woman, bearing of high dysphagia and pharyngolalic voice. The exploration showed a tumour emerging in lingual tonsil and spreading out to hypopharynx and larynx. No lymph nodes were observed. Its resistance to chemotherapy made necessary its surgical removal (AU)


Assuntos
Adulto , Feminino , Humanos , Linfoma de Burkitt/complicações , Tonsila Palatina/patologia , Transtornos de Deglutição/etiologia , Linfoma de Burkitt/tratamento farmacológico , Linfoma de Burkitt/patologia , Resistencia a Medicamentos Antineoplásicos , Soropositividade para HIV/complicações
12.
Acta otorrinolaringol. esp ; 53(10): 707-717, dic. 2002. ilus, tab, graf
Artigo em Es | IBECS | ID: ibc-16176

RESUMO

Objetivo: Con la introducción de los Potenciales Evocados Auditivos de estado estable (PEAee), se hace necesario el establecimiento de las posibilidades y limitaciones de esta técnica para establecer su valor en el ámbito clínico. Mediante este trabajo se han comparado los umbrales auditivos obtenidos mediante PEAee con los umbrales conductuales aportados por la Audiometría Tonal Liminar (ATL) al considerar estos últimos como "gold standard". Materiales y métodos: Se obtuvieron los umbrales auditivos a una muestra de 84 oídos mediante PEAee a multifrecuencia de forma monoaural, y los umbrales conductuales mediante ATL. Los valores obtenidos se procesaron para calcular sus correlaciones y otras variables. Resultados: Los PEAee aportan umbrales algo mayores de los umbrales conductuales, con una diferencia media de 23 dB. Esta diferencia disminuye en frecuencias altas y sujetos hipoacúsicos. Conclusión: Los PEAee a multifrecuencia posibilitan la determinación de umbrales auditivos objetivamente, siendo más aproximados al aumentar la frecuencia de estimulación y el grado de hipoacusia. Se hace necesario el establecimiento de protocolos de exploración que aseguren el máximo rendimiento de la técnica. Mediante este trabajo proponemos un algoritmo diagnóstico con el que llevarla a cabo (AU)


OBJECTIVE: Since the set up of Steady-State Auditory Evoked Potentials as a routine technique, it has became necessary the establishment of clinic capabilities and limitations. In this study, we have compared SSEP to behavioural thresholds, considering the last one as "gold standard" technique. MATERIALS AND METHODS: We have recorded SSEP to multiple frequencies and behavioural thresholds in 84 ears. The obtained data were statistically processed to obtain correlations and others indicators. RESULTS: SSEP thresholds are slightly higher than behavioural, whose average difference was calculated as 23 dB. It is worth to note that this difference diminishes at high frequencies and hearing loss cases. CONCLUSIONS: SSEP to multiple frequencies technique is capable to determine auditory thresholds accurately, being closer to the behavioural value at high frequencies and high threshold values. It is necessary the establishment of exploration protocols to assure the highest accuracy of the system. In this work, a diagnostic algorithm has been proposed to reach better results by using SSEP (AU)


Assuntos
Pessoa de Meia-Idade , Criança , Adulto , Adolescente , Idoso , Masculino , Feminino , Humanos , Limiar Auditivo/fisiologia , Potenciais Evocados Auditivos , Transtornos da Audição/diagnóstico , Algoritmos
13.
Acta Otorrinolaringol Esp ; 53(5): 371-6, 2002 May.
Artigo em Espanhol | MEDLINE | ID: mdl-12185872

RESUMO

We report two cases of sudden deafness which appeared during vaso-occlusive crisis of a sickle cell anaemia (homozygous form of disease) and a sickle cell trait (heterozygous form) in two males aged sixteen and twenty-two, respectively. A high erythrocyte aggregability and low deformability were proved in both young men. Although hearing disorders have been reported in this disease, a sudden onset is not common. The treatment used was useful in the removal of painful crisis and infections, but deafness did not improve in either of then.


Assuntos
Anemia Falciforme/complicações , Surdez/etiologia , Perda Auditiva Neurossensorial/etiologia , Perda Auditiva Súbita/etiologia , Traço Falciforme/complicações , Dor Abdominal/etiologia , Adolescente , Adulto , Medicina Aeroespacial , Anemia Falciforme/sangue , Viscosidade Sanguínea , Hipóxia Celular , Surdez/fisiopatologia , Agregação Eritrocítica , Deformação Eritrocítica , Necrose da Cabeça do Fêmur/etiologia , Perda Auditiva Neurossensorial/fisiopatologia , Perda Auditiva Súbita/fisiopatologia , Humanos , Hipóxia/complicações , Masculino , Osteomielite/complicações , Traço Falciforme/sangue , Infecções Estafilocócicas/complicações
14.
Acta Otorrinolaringol Esp ; 53(4): 269-80, 2002 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-12185904

RESUMO

In order to evaluate the clinical and functional effectiveness of uvulopalatopharyngoplasty (UPPP) in chronic roncopathy, we studied the subjective improvement of operated patients and compared to pulsioximetry findings before and after surgery. A follow-up was made on 72 patients entitled of chronic roncopathy--51 with obstructive sleep apnea syndrome (OSAS) and 21 with simple snoring-, for a mean period of time of 41 months. Preoperatory study included on ENT exploration, fibre optic endoscopy, Müller maneuver, pharyngeal CT, value of daytime sleepiness with Epworth's scale, espirometry and pulsioximetry, and the postoperatory study included of pulsioximetry and a health questionnaire over snoring and daytime sleepiness. Snoring improved or disappeared in 13 of 21 patients (61.8%), and daytime sleepiness did it in 26 of 39 (66.6%). Therapeutic failure in snoring was mainly due to an increase in the body mass index. After UPPP in OSAS, only 21 patients (41.1%) showed all positive response criteria (decrease into ODI > or = 50% or in absolute values < 6, CT 90% < 1%, and SaO2 Min > or = 85%). UPPP failed in long term evaluation in the rest of individuals. Patient selection is mandatory to optimize clinical response of UPPP for snoring, without OSAS success depends on body mass index, respiratory disturbances ratios and the eventual presence of another upper airways collapses below velopharyngeal segment.


Assuntos
Procedimentos Cirúrgicos Otorrinolaringológicos/métodos , Palato Mole/cirurgia , Ronco/diagnóstico , Ronco/cirurgia , Úvula/cirurgia , Adulto , Distúrbios do Sono por Sonolência Excessiva/diagnóstico , Distúrbios do Sono por Sonolência Excessiva/etiologia , Feminino , Seguimentos , Nível de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Apneia Obstrutiva do Sono/complicações , Ronco/complicações , Inquéritos e Questionários , Tempo , Resultado do Tratamento
15.
Rev. esp. geriatr. gerontol. (Ed. impr.) ; 37(4): 216-221, jul. 2002. tab, graf
Artigo em ES | IBECS | ID: ibc-16222

RESUMO

OBJETIVOS: Valorar en individuos mayores de 65 años la eventual correlación entre predisposición a la presbiacusia e hiperviscosidad sanguínea. PACIENTES Y MÉTODOS: Estudio sobre 20 individuos normooyentes y 80 afectos de hipoacusia perceptiva bilateral simétrica y progresiva de los siguientes parámetros hemorreológicos: filtrabilidad, deformabilidad y agregabilidad eritrocitaria, así como viscosidad en sangre total a diferentes velocidades de cizallamiento. Todos ellos con más de 65 años de edad. RESULTADOS: Se detectaron diferencias estadísticamente significativas en todos los parámetros medidos comparando individuos normooyentes y presbiacúsicos. La pérdida auditiva media se correlacionó de forma significativa con elevaciones en la agregabilidad eritrocitaria y con la viscosidad en sangre total a velocidades de cizallamiento altas (p< 0,01). Este último valor se correlacionó además con la pérdida auditiva en 2 kHz, y el descenso en la filtrabilidad eritrocitaria lo hizo con las pérdidas en 4 y 8 kHz. CONCLUSIONES: Existe un marcado deterioro en las propiedades viscoelásticas de la sangre entre sujetos mayores de 65 años afectos de presbiacusia. Un tratamiento preventivo de estas modificaciones podría reducir la incidencia de hipoacusia progresiva degenerativa en ancianos (AU)


Assuntos
Idoso , Idoso de 80 Anos ou mais , Humanos , Viscosidade Sanguínea , Presbiacusia/sangue , Presbiacusia/etiologia , Estudos de Casos e Controles , Envelhecimento/fisiologia
16.
Acta Otorrinolaringol Esp ; 53(3): 221-4, 2002 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-12073683

RESUMO

Diabetes mellitus is considered a risk factor for sensorineural sudden deafness. Its pathogenesis remains unknown. However, the physiopathological implication of a hyperviscosity syndrome in diabetics and patients bearing of sudden deafness can mean the nexus between the two entities. Total blood viscosity and erythrocyte adhesion were haemorheological parameters significatively higher in blood of diabetics with sudden deafness than in normal hearing controls. Moreover, erythrocyte filterability and deformability were lower in diabetics, but it was not statistically significative. These findings help to guide therapy in these patients towards specific measures to improve blood viscoelastic properties.


Assuntos
Viscosidade Sanguínea , Complicações do Diabetes , Perda Auditiva Neurossensorial/complicações , Perda Auditiva Súbita/complicações , Doenças Hematológicas/complicações , Humanos , Pessoa de Meia-Idade , Síndrome
17.
Acta otorrinolaringol. esp ; 53(5): 371-376, mayo 2002. ilus, graf
Artigo em Es | IBECS | ID: ibc-12018

RESUMO

Presentamos los dos casos de sordera súbita acontecidos durante el desarrollo de sendas crisis vasooclusivas en el contexto de una anemia de células falciformes (forma homocigota de la drepanocitosis) y de un rasgo drepanocítico (forma heterocigota) en dos varones de 16 y 22 años de edad, respectivamente. En ambos casos se constató el aumento en la agregabilidad de los eritrocitos y la disminución en su deformabilidad. Aunque está reconocida la afectación auditiva en esta enfermedad, la rapidez de instauración es rara. El tratamiento empleado alivió las crisis dolorosas y erradicó las infecciones, pero la hipoacusia resultó irreversible (AU)


We report two cases of sudden deafness which appeared during vaso-occlusive crisis of a sickle cell anaemia (homozygous form of disease) and a sickle cell trait (heterozygous form) in two males aged sixteen and twenty-two, respectively. A high erythrocyte aggregability and low deformability were proved in both young men. Although hearing disorders have been reported in this disease, a sudden onset is not common. The treatment used was useful in the removal of painful crisis and infections, but deafness did not improve in either of then (AU)


Assuntos
Adulto , Adolescente , Masculino , Humanos , Infecções Estafilocócicas , Osteomielite , Perda Auditiva Súbita , Surdez/etiologia , Anemia Falciforme , Perda Auditiva Neurossensorial , Traço Falciforme/complicações , Hipóxia Celular , Dor Abdominal/etiologia , Deformação Eritrocítica , Agregação Eritrocítica
18.
An Esp Pediatr ; 56(4): 310-7, 2002 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-11927098

RESUMO

BACKGROUND AND OBJECTIVES: Oxidative stress secondary to infant tonsillar infection produces the expression of local and systemic antioxidants. Its determination seems to be useful as a marker of tonsillar suffering before tonsillectomy but is currently unknown. The aim of this study was to determine the evolution of this parameter in tonsillectomized children during a long-term follow-up. METHODS: One hundred thirty-six children underwent tonsillectomy, 46 for tonsillar hypertrophy without infection and 90 for recurrent tonsillitis. Superoxide dismutase (SOD) concentrations were measured before tonsillectomy and at 6, 12, 24 and 36 months post-tonsillectomy. RESULTS: Infection provoked significantly higher SOD concentrations than tonsillar hypertrophy in tonsillar tissue (223.06 30.46 vs 156.39 54.05 U/l, p < 0.001) and in blood (1124.91 141.73 vs 1007.19 97.03 U/gr Hb, p < 0.001). There was a strong correlation between tonsillar and erythrocyte concentrations. During the 3-year follow-up, SOD concentrations in blood progressively decreased until stabilizing in all patients. Stabilization was reached at 6 months post-tonsillectomy in the group with tonsillar hypertrophy and at 2 years in the group with infection. Children with recurrent tonsillitis consistently showed higher SOD concentrations in blood throughout the follow-up. CONCLUSIONS: Oxidative damage in tonsillar tissue results from the incidence and severity of focal infections. Tonsillectomy reduces SOD levels but, as a consequence of oxidative stress, these do not return to normal.


Assuntos
Eritrócitos/enzimologia , Estresse Oxidativo , Tonsila Palatina/enzimologia , Superóxido Dismutase/análise , Tonsilite/enzimologia , Adolescente , Fatores Etários , Criança , Pré-Escolar , Seguimentos , Humanos , Recidiva , Espectrofotometria , Superóxido Dismutase/sangue , Fatores de Tempo , Tonsilectomia , Tonsilite/cirurgia
19.
An. esp. pediatr. (Ed. impr) ; 56(4): 310-317, abr. 2002.
Artigo em Es | IBECS | ID: ibc-6702

RESUMO

Antecedentes y objetivos: El estrés oxidativo de la infección amigdalar infantil determina la expresión de antioxidantes locales y sistémicos. Su determinación parece tener valor como marcador de padecimiento amigdalar previo a la amigdalectomía, pero permanece desconocida, y es ésa nuestra meta, la evolución de este parámetro en niños intervenidos y seguidos a largo plazo. Métodos: Se estudiaron 136 niños amigdalectomizados, 46 por hipertrofia amigdalar sin infección, y 90 por amigdalitis recurrente. En ellos se midieron concentraciones de superóxido dismutasa (SOD) preoperatoria, así como a los 6, 12, 24 y 36 meses postamigdalectomía. Resultados: La infección generó concentraciones significativamente mayores que la hipertrofia amigdalar en tejido amigdalar (223,06 30,46 frente a 156,39 54,05 U/l; p < 0,001) y sangre (1.124,91 141,73 frente a 1.007,19 97,03 U/g Hb; p < 0,001), existiendo muy buena correlación entre las concentraciones amigdalares y eritrocitarias en ambos grupos. El seguimiento a 3 años permitió detectar una progresiva tendencia al descenso en los niveles de SOD en sangre en todos los casos hasta su estabilización. Este estado se alcanza antes en el grupo con hipertrofia amigdalar a los 6 meses postamigdalectomía, y a los 2 años en el de infecciones. En cualquier caso, en su seguimiento postamigdalectomía los niños con amigdalitis de repetición siempre mostraron concentraciones de SOD más altas. Conclusiones: El daño oxidativo en tejido amigdalar resulta de la incidencia y gravedad de las infecciones focales, y la anulación de éstas redunda en un descenso en los niveles de SOD que no llegan a la normalización, a modo de registro inmune frente a una agresión oxidativa (AU)


Assuntos
Criança , Pré-Escolar , Adolescente , Masculino , Lactente , Feminino , Humanos , Estresse Oxidativo , Espectrofotometria , Tonsila Palatina , Tonsilectomia , Superóxido Dismutase , Tonsilite , Fatores de Tempo , Estudos de Casos e Controles , Infecções Pneumocócicas , Recidiva , Prognóstico , Estudos Retrospectivos , Fatores Etários , Eritrócitos , Seguimentos
20.
Acta otorrinolaringol. esp ; 53(4): 269-280, abr. 2002. tab, graf
Artigo em Es | IBECS | ID: ibc-12008

RESUMO

Con objeto de valorar la eficacia clínica y funcional de la uvulopalatofaringoplastia (UPPP) en la roncopatía crónica, se estudió el grado de mejoría subjetiva de pacientes intervenidos y se comparó con los hallazgos pulsioximétricos pre y postoperatorios. Se efectuó seguimiento sobre 72 pacientes con roncopatía crónica -51 con síndrome de apnea obstructiva del sueño (SAOS) y 21 con ronquido simple (RS)-, durante un período medio de 41 meses. Se efectuó estudio preoperatorio mediante exploración ORL, nasofibroscopia, maniobra de Müller, escala de Epworth, TC faríngeo, espirometría y pulsioximetría nocturna, y postoperatorio mediante pulsioximetría nocturna y un cuestionario de salud sobre el ronquido y la hipersomnia diurna mediante escala de Epworth. Existió mejoría o curación del ronquido en 13 de los 21 pacientes afectos (61,8 por ciento) y de la hipersomnia en 26 de 39 (66,6 por ciento). El fracaso terapéutico en el ronquido simple se asoció al aumento del índice de masa corporal. En el SAOS, tras la UPPP, sólo se cumplieron en 21 pacientes (41,1 por ciento) todos los criterios de respuesta (reducción del ODI 50 por ciento, reducción del ODI <6, CT 90 por ciento <1 por ciento, y SaO2 Min 85 por ciento). A largo plazo la UPPP fracasó en el resto de individuos. Concluimos señalando que se deben seleccionar los pacientes para UPPP incluso en caso de RS y que el fracaso de la UPPP en el SAOS está en función del índice de masa corporal, los índices elevados de disturbios respiratorios y la existencia de otros segmentos colapsables de las vías altas caudalmente al velo palatino (AU)


In order to evaluate the clinical and functional effectiveness of uvulopalatopharyngoplasty (UPPP) in chronic roncopathy, we studied the subjective improvement of operated patients and compared to pulsioximetry findings before and after surgery. A follow-up was made on 72 patients entitled of chronic roncopathy--51 with obstructive sleep apnea syndrome (OSAS) and 21 with simple snoring-, for a mean period of time of 41 months. Preoperatory study included on ENT exploration, fibre optic endoscopy, Müller maneuver, pharyngeal CT, value of daytime sleepiness with Epworth's scale, espirometry and pulsioximetry, and the postoperatory study included of pulsioximetry and a health questionnaire over snoring and daytime sleepiness. Snoring improved or disappeared in 13 of 21 patients (61.8%), and daytime sleepiness did it in 26 of 39 (66.6%). Therapeutic failure in snoring was mainly due to an increase in the body mass index. After UPPP in OSAS, only 21 patients (41.1%) showed all positive response criteria (decrease into ODI > or = 50% or in absolute values < 6, CT 90% < 1%, and SaO2 Min > or = 85%). UPPP failed in long term evaluation in the rest of individuals. Patient selection is mandatory to optimize clinical response of UPPP for snoring, without OSAS success depends on body mass index, respiratory disturbances ratios and the eventual presence of another upper airways collapses below velopharyngeal segment (AU)


Assuntos
Pessoa de Meia-Idade , Adulto , Masculino , Feminino , Humanos , Ronco/diagnóstico , Procedimentos Cirúrgicos Otorrinolaringológicos/métodos , Palato Mole/cirurgia , Nível de Saúde , Úvula/cirurgia , Tempo , Resultado do Tratamento , Inquéritos e Questionários , Apneia Obstrutiva do Sono/complicações , Distúrbios do Sono por Sonolência Excessiva , Seguimentos , Índice de Gravidade de Doença
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